A Khodamoradi; E Talebi Garakani; F Mir Mohammad Rezaei; R Fathi
Abstract
Aim: Excessed energy is stored as triacylglycerol (TAG) in adipose tissue within various organs. In order to reduce excessed fat storage, the utilization of fat storage must be increased to produce energy. The purpose of this study was to evaluate the effects of 8 weeks progressive resistance training ...
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Aim: Excessed energy is stored as triacylglycerol (TAG) in adipose tissue within various organs. In order to reduce excessed fat storage, the utilization of fat storage must be increased to produce energy. The purpose of this study was to evaluate the effects of 8 weeks progressive resistance training on expression of proteins involved in skeletal muscle tissue lipolysis in rats feed with sucrose solution. Method: 32 male Wistar rats (6-8 weeks) were randomly divided into two groups, the first group took sucrose solution 30%, the second group did not. After 4 weeks, each group divided into exercise and control groups. Exercise groups performed a progressive resistance training protocol 3 days per week for 8 weeks. Tissue samples were taken 2 days after the last session. HSL, Perilipin and LXRα protein expression were determined by Western blot. To evaluate the difference between the variable and the interaction between them, two-way ANOVA at the significant level of P˂0.05 was used. Results: Protein levels of HSL and Perilipin were increased in the exercise group compared to control (P˂0.001), but LXRα levels were unchanged. The effect of sucrose solution alone and the interaction between the consumption of sucrose and progressive resistance training on the expression of these proteins in muscle tissue were not significant. Conclusion: The results show that although the 8 weeks of progressive resistance training significantly increased the expression of some proteins involved in lipolysis, but these changes are not related to the consumption of sucrose solution.